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              1. 亚洲精品1区2区3区_国产黄色三级_蜜臀av人妻_日本中文字幕有码_来一水AV@lysav

                當(dāng)前位置:網(wǎng)站首頁產(chǎn)品展示抗體多克隆抗體 > YP-Ab-00510Rad51 Polyclonal Antibody
                Rad51 Polyclonal Antibody

                Rad51 Polyclonal Antibody

                簡要描述:Rad51 Polyclonal Antibody
                宿主: Polyclonal, Rabbit,IgG
                反應(yīng)性: Human;Mouse
                應(yīng)用: WB;IHC;IF;ELISA

                產(chǎn)品型號(hào): YP-Ab-00510

                所屬分類:多克隆抗體

                更新時(shí)間:2024-11-01

                詳細(xì)說明:

                Rad51 Polyclonal Antibody

                抗體,也叫免疫球蛋白(Ig),是一種能特異性結(jié)合抗原的糖蛋白,而抗原是在易感染動(dòng)物體內(nèi)引發(fā)抗體產(chǎn)生的物質(zhì)。在體內(nèi),抗體是由于外源性分子的侵襲而產(chǎn)生的。抗體以一個(gè)或者多個(gè)Y字形單體存在,每個(gè)Y字形單體由4條多肽鏈組成,包含兩條相同的重鏈和兩條相同的輕鏈。輕鏈和重鏈?zhǔn)歉鶕?jù)它們的分子量大小來命名的。Y字形結(jié)構(gòu)的頂端是可變區(qū),為抗原結(jié)合部位。任何一個(gè)抗體的輕鏈都可以分為κ或λ型(基于小分子多肽結(jié)構(gòu)上的差異),每一個(gè)抗體的重鏈則決定了它的類或型。

                產(chǎn)品詳情
                Rad51 Polyclonal Antibody detects endogenous levels of Rad51 protein.
                免疫原詳細(xì)信息
                The antiserum was produced against synthesized peptide derived from human RAD51. AA range:281-330
                相關(guān)試劑
                Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
                背景

                The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]


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                備注:圖片僅供參考。僅供科研,不可用于臨床。

                Rad51D Polyclonal Antibody




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